Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Causal Associations between Pre-pregnancy Obesity Traits and Hypertensive Disorders of Pregnancy: A Two-Sample Mendelian Randomization Analyses.

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC - 1 Mar 2026

Hu Mengjin, Xia Jinggang, Yin Chunlin

Abstract excerpt

OBJECTIVE: To investigate potential causal effects of pre-pregnancy obesity traits on hypertensive disorders of pregnancy-gestational hypertension, preeclampsia, and eclampsia-using genetic epidemiology approaches. METHODS: We performed a comprehensive 2-sample Mendelian randomization (MR) analysis leveraging summary statistics from large-scale genome-wide association studies. Eleven adiposity-related exposure...

Topics

Humans
Pregnancy
Female
Mendelian Randomization Analysis
Hypertension, Pregnancy-Induced
Pre-Eclampsia
Obesity
Genome-Wide Association Study
Genetic Predisposition to Disease
Body Mass Index

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pediatric Obesity

Source

Identifiers

PMID: 41005619
DOI: 10.1016/j.jogc.2025.103070

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Causal Associations between Pre-pregnancy Obesity Traits and Hypertensive Disorders of Pregnancy: A Two-Sample Mendelian Randomization Analyses.PMID 41005619Read ↗

Phenome-Wide Investigation of the Causal Associations Between Pre-Pregnancy Obesity Traits and Gestational Diabetes: A Two-Sample Mendelian Randomization Analyses.Semantic proximity Read ↗

Childhood obesity and hypertension in pregnancy: a two-sample Mendelian randomization analysis.Semantic proximity Read ↗

Obesity and risk of gestational diabetes mellitus: A two-sample Mendelian randomization study.Semantic proximity Read ↗

Genetically determined body mass index and maternal outcomes of pregnancy: a two-sample Mendelian randomization studySemantic proximity Read ↗

Obesity and risk of female reproductive conditions: A Mendelian randomisation studySemantic proximity Read ↗

Genetically predicted body mass index and maternal outcomes of pregnancy: A two-sample Mendelian randomisation study.Semantic proximity Read ↗

The role of obesity in female reproductive conditions: A Mendelian Randomisation studySemantic proximity Read ↗

Sex- and time-specific associations of obesity with glycaemic traits: A two-step multivariate Mendelian randomization study.Semantic proximity Read ↗

Causal pathways in preeclampsia: a Mendelian randomization study in European populations.Semantic proximity Read ↗

Birth weight, childhood obesity and risk of hypertension: a Mendelian randomization study.Semantic proximity Read ↗

Maternal Hypertension Increases Risk of Preeclampsia and Low Fetal Birthweight: Genetic Evidence From a Mendelian Randomization Study.Semantic proximity Read ↗

Relationships between body fat distribution and metabolic syndrome traits and outcomes: a Mendelian Randomization studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.