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Article

Causal Effect of Visceral Adipose Tissue Accumulation on the Human Longevity: A Mendelian Randomization Study.

Frontiers in endocrinology - 1 Jan 2021

Yan Bin, Yang Jian, Zhao Binbin, Wu Yanhua, Bai Ling, Ma Xiancang

Abstract excerpt

Objective: Observational studies have demonstrated a close relationship between obesity and longevity. The aim of this Mendelian randomization (MR) study is to investigate whether genetic determinants of visceral adipose tissue (VAT) accumulation are causally associated with longevity. Methods: In this two-sample MR study, we used summary data of genetic determinants (single-nucleotide polymorphisms; p < 5 ×...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34539575
DOI: 10.3389/fendo.2021.722187
PMCID: PMC8440971

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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