Article
Mendelian randomization study reveals a causal relationship between rheumatoid arthritis and risk for pre-eclampsia.
Frontiers in immunology - 1 Jan 2022
Zhang Dingyi, Hu Ying, Guo Weijie, Song Yang, Yang Lin, Yang Shuhan, Ou Taoaixin, Liu Yanxu, Zhang Yaoyao
Abstract excerpt
Background: Epidemiological observational studies have investigated the relationship between rheumatoid arthritis(RA) and pre-eclampsia, but no consistent conclusions were obtained due to various limitations. Hence, we conducted a two-sample mendelian randomization analysis to evaluate the potential causal effect of RA on pre-eclampsia. Methods: Summary-level statistics for RA were derived from a large-scale...
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