Article
Bone marrow derived long-lived plasma cell phenotypes are heterogeneous and can change in culture.
Transplant immunology - 1 Dec 2022
Mujtahedi Syed S, Yigitbilek Furkan, Benavides Xiomara, Merzkani Massini A, Ozdogan Elif, Abozied Omar, Moore Natalie A, Park Walter D, Stegall Mark D
Abstract excerpt
Bone marrow-derived long-lived plasma cells (LLPCs) are thought to be a major source of alloantibody in sensitized transplant patients. However, studies of LLPCs have been hampered not only by the fact that they are rare and difficult to isolate and culture but also due to the lack of consensus regarding a definitive cell-surface phenotype. The goal of the current study was to determine if LLPCs have a specific,...
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