Article
CD38 low IgG-secreting cells are precursors of various CD38 high-expressing plasma cell populations.
Journal of leukocyte biology - 1 Jun 2004
Arce Sergio, Luger Elke, Muehlinghaus Gwendolin, Cassese Giuliana, Hauser Anja, Horst Alexander, Lehnert Katja, Odendahl Marcus, Hönemann Dirk, Heller Karl-Dieter, Kleinschmidt Harald, Berek Claudia, Dörner Thomas, Krenn Veit, Hiepe Falk, Bargou Ralf, Radbruch Andreas, Manz Rudolf A
Abstract excerpt
Despite the important role immunoglobulin G (IgG)-secreting plasma cells play in memory immune responses, the differentiation and homeostasis of these cells are not completely understood. Here, we studied the differentiation of human IgG-secreting cells ex vivo and in vitro, identifying these cells by the cellular affinity matrix technology. Several subpopulations of IgG-secreting cells were identified among the...
Topics
- ADP-ribosyl Cyclase
- ADP-ribosyl Cyclase 1
- Antigens, CD
- Antigens, CD19
- B-Lymphocyte Subsets
- Bone Marrow
- Cell Differentiation
- Cell Movement
- Humans