Article
Plasma cells in immunopathology: concepts and therapeutic strategies.
Seminars in immunopathology - 1 May 2014
Tiburzy Benjamin, Kulkarni Upasana, Hauser Anja Erika, Abram Melanie, Manz Rudolf Armin
Abstract excerpt
Plasma cells are terminally differentiated B cells that secrete antibodies, important for immune protection, but also contribute to any allergic and autoimmune disease. There is increasing evidence that plasma cell populations exhibit a considerable degree of heterogeneity with respect to their immunophenotype, migration behavior, lifetime, and susceptibility to immunosuppressive drugs. Pathogenic long-lived...
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