Article

SARS-CoV-2 specific plasma cells acquire the phenotype of long-lived plasma cells in the human bone marrow

2022-08-12

Abstract excerpt

Establishment of long-lived plasma cells (PC) in the bone marrow (BM) is important for the development of long-term specific humoral immunity. While SARS-CoV-2-specific, resting, affinity-matured, IgG-secreting plasma cells were described in human bone marrow approx. 6-7 months after infection or vaccination, the long-term durability of these PC remains unclear. We here show that approximately 20% of SARS-CoV-2-sp...

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Literature Corpus work: 84160a7b-0e8b-5ea6-9b2d-62fdf375b6b9
DOI: 10.1101/2022.08.11.503574

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