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Article

CSF ctDNA analysis guides molecular reclassification of diffuse glioma patients.

Journal of neuro-oncology - 21 May 2026

Arjuna Srividya, Pirhoushiaran Maryam, Bueno Angel, Sanchez-Espitia Alexander, Tavakkol Elham, Khalaj Kamand, Shah Mauli, Wang Isabel, Balar Ashish P, Dono Antonio, Duose Dzifa, Nguyen Sophia, Kamali Arash, Luthra Rajyalakshmi, Patel Chirag B, Prabhu Sujit S, Lang Frederick F, Esquenazi Yoshua, Ballester Leomar Y

Abstract excerpt

BACKGROUND: There is a critical need for better strategies to diagnose and monitor patients with gliomas. Liquid biopsies are less invasive than tissue biopsies and are amenable to serial collection at multiple timepoints. However, the analysis of circulating tumor DNA (ctDNA) in cerebrospinal fluid (CSF) from patients with gliomas remains underutilized in clinical practice due to technical challenges. METHODS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42168657
DOI: 10.1007/s11060-026-05623-2
PMCID: PMC13194200

Genes

EGFR
IDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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