Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular Diagnosis of Diffuse Gliomas through Sequencing of Cell-Free Circulating Tumor DNA from Cerebrospinal Fluid.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jun 2018

Martínez-Ricarte Francisco, Mayor Regina, Martínez-Sáez Elena, Rubio-Pérez Carlota, Pineda Estela, Cordero Esteban, Cicuéndez Marta, Poca Maria A, López-Bigas Nuria, Ramon Y Cajal Santiago, Vieito María, Carles Joan, Tabernero Josep, Vivancos Ana, Gallego Soledad, Graus Francesc, Sahuquillo Juan, Seoane Joan

Abstract excerpt

Purpose: Diffuse gliomas are the most common primary tumor of the brain and include different subtypes with diverse prognosis. The genomic characterization of diffuse gliomas facilitates their molecular diagnosis. The anatomical localization of diffuse gliomas complicates access to tumor specimens for diagnosis, in some cases incurring high-risk surgical procedures and stereotactic biopsies. Recently, cell-free...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Circulating Tumor DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genomics

Share to Glioma

Share to Immunohistochemistry

Share to In Situ Hybridization, Fluorescence

Share to Kaplan-Meier Estimate

Share to Magnetic Resonance Imaging

Share to Molecular Diagnostic Techniques

Source

Identifiers

PMID: 29615461
DOI: 10.1158/1078-0432.CCR-17-3800

Genes

ATRX
IDH1
IDH2
TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular Diagnosis of Diffuse Gliomas through Sequencing of Cell-Free Circulating Tumor DNA from Cerebrospinal Fluid.PMID 29615461Read ↗

Molecular diagnosis of diffuse glioma using a chip-based digital PCR system to analyze IDH, TERT, and H3 mutations in the cerebrospinal fluid.Semantic proximity Read ↗

CSF ctDNA analysis guides molecular reclassification of diffuse glioma patients.Semantic proximity Read ↗

Clinical utility of plasma cell-free DNA (cfDNA) in diffuse gliomas for the detection of IDH1 R132H mutation.Semantic proximity Read ↗

Sensitive and rapid detection of TERT promoter and IDH mutations in diffuse gliomas.Semantic proximity Read ↗

Diffuse Gliomas of the Brainstem and Cerebellum in Adults Show Molecular HeterogeneitySemantic proximity Read ↗

A Custom DNA-Based NGS Panel for the Molecular Characterization of Patients With Diffuse Gliomas: Diagnostic and Therapeutic ApplicationsSemantic proximity Read ↗

The Evolving Role of Molecular Markers in the Diagnosis and Management of Diffuse GliomaSemantic proximity Read ↗

Diffuse Gliomas for Nonneuropathologists: The New Integrated Molecular Diagnostics.Semantic proximity Read ↗

Cerebrospinal fluid-derived genomic alterations tracking gliomaSemantic proximity Read ↗

A Novel Type of IDH-wildtype Glioma Characterized by Gliomatosis Cerebri-like Growth Pattern, TERT Promoter Mutation, and Distinct Epigenetic Profile.Semantic proximity Read ↗

Beyond IDH-Mutation: Emerging Molecular Diagnostic and Prognostic Features in Adult Diffuse GliomasSemantic proximity Read ↗

Cerebrospinal fluid tumor DNA for liquid biopsy in glioma patients' management: Close to the clinic?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.