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Case-case genome-wide association analysis identifying genetic loci with divergent effects on Crohn's disease and ulcerative colitis.

Human molecular genetics - 27 Jan 2023

Jung Seulgi, Kim Yongjae, Park Dohoon, Lee Yoonho, Park Sojung, Baek Jiwon, Hwang Sung Wook, Park Sang Hyoung, Yang Suk-Kyun, Ye Byong Duk, Han Buhm, Song Kyuyoung, Lee Ho-Su

Abstract excerpt

Crohn's disease (CD) and ulcerative colitis (UC), two major subtypes of inflammatory bowel disease, show substantial differences in their clinical course and treatment response. To identify the genetic factors underlying the distinct characteristics of these two diseases, we performed a genome-wide association study (GWAS) between CD (n = 2359) and UC (n = 2175) in a Korean population, followed by replication in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36164742
DOI: 10.1093/hmg/ddac241

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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