Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort.

The American journal of gastroenterology - 1 Mar 2009

Weersma Rinse K, Stokkers Pieter C F, Cleynen Isabelle, Wolfkamp Simone C S, Henckaerts Liesbet, Schreiber Stefan, Dijkstra Gerard, Franke Andre, Nolte Ilja M, Rutgeerts Paul, Wijmenga Cisca, Vermeire Séverine

Abstract excerpt

OBJECTIVES: Inflammatory bowel diseases (IBD)-Crohn's disease (CD) and ulcerative colitis (UC)-are chronic gastrointestinal inflammatory disorders with a complex genetic background. A genome-wide association scan by the Wellcome Trust Case Control Consortium (WTCCC) recently identified several novel susceptibility loci. METHODS: We performed a large replication study in 2,731 Dutch and Belgian IBD patients (1,656...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy-Related Proteins
Share to Belgium

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Colitis, Ulcerative

Share to GTP-Binding Proteins

Share to Guanine Nucleotide Exchange Factors

Share to Nod2 Signaling Adaptor Protein

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 2

Share to Receptors, Interleukin

Source

Identifiers

PMID: 19174780
DOI: 10.1038/ajg.2008.112

Genes

CCNY
HERC2
IRGM
NELL1
PTPN2
RCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort.PMID 19174780Read ↗

Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations.Semantic proximity Read ↗

Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis.Semantic proximity Read ↗

Case-case genome-wide association analysis identifying genetic loci with divergent effects on Crohn's disease and ulcerative colitis.Semantic proximity Read ↗

Meta-analysis of published studies identified eight additional common susceptibility loci for Crohn's disease and ulcerative colitis.Semantic proximity Read ↗

The expanding universe of inflammatory bowel disease genetics.Semantic proximity Read ↗

ATG16L1 and IL23R are associated with inflammatory bowel diseases but not with celiac disease in the Netherlands.Semantic proximity Read ↗

IL23R R381Q and ATG16L1 T300A are strongly associated with Crohn's disease in a study of New Zealand Caucasians with inflammatory bowel disease.Semantic proximity Read ↗

Rare and common variant discovery in complex disease: the IBD case studySemantic proximity Read ↗

Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci.Semantic proximity Read ↗

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease.Semantic proximity Read ↗

Replication study of ulcerative colitis risk loci in a Lithuanian-Latvian case-control sample.Semantic proximity Read ↗

Genetics of inflammatory bowel disease: clues to pathogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.