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Article

Limited evidence for blood eQTLs in human sexual dimorphism.

Genome medicine - 11 Aug 2022

Porcu Eleonora, Claringbould Annique, Weihs Antoine, Lepik Kaido, Richardson Tom G, Völker Uwe, Santoni Federico A, Teumer Alexander, Franke Lude, Reymond Alexandre, Kutalik Zoltán

Abstract excerpt

BACKGROUND: The genetic underpinning of sexual dimorphism is very poorly understood. The prevalence of many diseases differs between men and women, which could be in part caused by sex-specific genetic effects. Nevertheless, only a few published genome-wide association studies (GWAS) were performed separately in each sex. The reported enrichment of expression quantitative trait loci (eQTLs) among GWAS-associated...

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Identifiers

PMID: 35953856
DOI: 10.1186/s13073-022-01088-w
PMCID: PMC9373355

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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