Article

Does Sex-Differential Gene Expression Drive Sex-Differential Selection in Humans?

2024-07-24

Abstract excerpt

Sex differences in human transcriptomes have been argued to drive sex-differential natural selection (SDS). Here, we show that previous evidence supporting this hypothesis has been largely unfounded. We develop a new method to test for a genome-wide relationship between sex differences in expression and selection on expression-influencing alleles (eQTLs). We apply it across 39 human tissues and find no evidence fo...

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Literature Corpus work: 0dab9920-4cc2-59e3-a20a-ff336dfcfe6e
DOI: 10.1101/2024.07.23.604672

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