Article
Sex differences in the human peripheral blood transcriptome.
BMC genomics - 17 Jan 2014
Jansen Rick, Batista Sandra, Brooks Andrew I, Tischfield Jay A, Willemsen Gonneke, van Grootheest Gerard, Hottenga Jouke-Jan, Milaneschi Yuri, Mbarek Hamdi, Madar Vered, Peyrot Wouter, Vink Jacqueline M, Verweij Cor L, de Geus Eco J C, Smit Johannes H, Wright Fred A, Sullivan Patrick F, Boomsma Dorret I, Penninx Brenda W J H
Abstract excerpt
BACKGROUND: Genomes of men and women differ in only a limited number of genes located on the sex chromosomes, whereas the transcriptome is far more sex-specific. Identification of sex-biased gene expression will contribute to understanding the molecular basis of sex-differences in complex traits and common diseases. RESULTS: Sex differences in the human peripheral blood transcriptome were characterized using...
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