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Article

Pharmacogenetics of the cytochromes P450: Selected pharmacological and toxicological aspects.

Advances in pharmacology (San Diego, Calif.) - 1 Jan 2022

Daly Ann K

Abstract excerpt

With the availability of detailed genomic data on all 57 human cytochrome P450 genes, it is clear that there is substantial variability in gene product activity with functionally significant polymorphisms reported across almost all isoforms. This article is concerned mainly with 13 P450 isoforms of particular relevance to xenobiotic metabolism. After brief review of the extent of polymorphism in each, the...

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Source

Identifiers

PMID: 35953163
DOI: 10.1016/bs.apha.2022.05.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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