Article
Bench to bedside: Pharmacogenomics, adverse drug interactions, and the cytochrome P450 system.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine - 1 Dec 2005
Sikka Rishi, Magauran Brendan, Ulrich Andrew, Shannon Michael
Abstract excerpt
As physicians attempt to improve the quality of health care, one area of particular concern has been preventable medical errors from adverse drug interactions. The cytochrome P450 family of enzymes has been implicated in a large number of these preventable, adverse drug interactions. This report reviews the basic biochemistry and pharmacogenomics underlying the reactions catalyzed by the cytochrome P450 family of...
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