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Article

Polymorphism of human cytochrome P450 enzymes and its clinical impact.

Drug metabolism reviews - 1 Jan 2009

Zhou Shu-Feng, Liu Jun-Ping, Chowbay Balram

Abstract excerpt

Pharmacogenetics is the study of how interindividual variations in the DNA sequence of specific genes affect drug response. This article highlights current pharmacogenetic knowledge on important human drug-metabolizing cytochrome P450s (CYPs) to understand the large interindividual variability in drug clearance and responses in clinical practice. The human CYP superfamily contains 57 functional genes and 58...

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Identifiers

PMID: 19514967
DOI: 10.1080/03602530902843483

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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