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Article

De novo emergence of SARS-CoV-2 spike mutations in immunosuppressed patients.

Transplant infectious disease : an official journal of the Transplantation Society - 1 Dec 2022

Simons Lacy M, Ozer Egon A, Gambut Stephanie, Dean Taylor J, Zhang Li, Bhimalli Pavan, Schneider Jeffrey R, Mamede João I, Ison Michael G, Karmali Reem, Gordon Leo I, Lorenzo-Redondo Ramon, Hultquist Judd F

Abstract excerpt

BACKGROUND: The continuing evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with decreased susceptibility to neutralizing antibodies is of clinical importance. Several spike mutations associated with immune escape have evolved independently in association with different variants of concern (VOCs). How and when these mutations arise is still unclear. We hypothesized that such...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35899968
DOI: 10.1111/tid.13914
PMCID: PMC9353292

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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