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Article

Intra-Host Evolution Provides for the Continuous Emergence of SARS-CoV-2 Variants.

mBio - 25 Apr 2023

Landis Justin T, Moorad Razia, Pluta Linda J, Caro-Vegas Carolina, McNamara Ryan P, Eason Anthony B, Bailey Aubrey, Villamor Femi Cleola S, Juarez Angelica, Wong Jason P, Yang Brian, Broussard Grant S, Damania Blossom, Dittmer Dirk P

Abstract excerpt

Variants of concern (VOC) in SARS-CoV-2 refer to viruses whose viral genomes differ from the ancestor virus by ≥3 single-nucleotide variants (SNVs) and that show the potential for higher transmissibility and/or worse clinical progression. VOC have the potential to disrupt ongoing public health measures and vaccine efforts. Still, too little is known regarding how frequently new viral variants emerge and under...

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Identifiers

PMID: 36786605
DOI: 10.1128/mbio.03448-22
PMCID: PMC10127995

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