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SARS-CoV-2 evolution during prolonged infection in immunocompromised patients

16 Feb 2024

Abstract excerpt

ABSTRACT Prolonged infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in immunocompromised patients provides an opportunity for viral evolution, potentially leading to the generation of new pathogenic variants. To investigate the pathways of viral evolution, we carried out a study on five patients experiencing prolonged SARS-CoV-2 infection (quantitative polymerase chain reaction-positive...

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PMID: 38364100
DOI: 10.1128/mbio.00110-24

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