Article

Intra-host viral populations of SARS-CoV-2 in immunosuppressed patients with hematologic cancers

2022-10-20

Abstract excerpt

Throughout the SARS-CoV-2 pandemic, several variants of concern (VOC) have been identified, many of which share recurrent mutations in the spike protein’s receptor binding domain (RBD). This region coincides with known epitopes and can therefore have an impact on immune escape. Protracted infections in immunosuppressed patients have been hypothesized to lead to an enrichment of such mutations and therefore drive e...

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Identifiers and source

Literature Corpus work: 34780bce-7763-554a-9962-402b6c261889
DOI: 10.1101/2022.10.19.512884

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