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Article

Targeted parallel DNA sequencing detects circulating tumor-associated variants of the mitochondrial and nuclear genomes in patients with neuroblastoma.

Cancer reports (Hoboken, N.J.) - 1 Jan 2023

Riehl Lara, Mulaw Medhanie, Kneer Katharina, Beer Meinhard, Beer Ambros, Barth Thomas F, Benes Vladimir, Schulte Johannes, Fischer Matthias, Debatin Klaus-Michael, Beltinger Christian

Abstract excerpt

BACKGROUND: The utility for liquid biopsy of tumor-associated circulating single-nucleotide variants, as opposed to mutations, of the mitochondrial (mt) and nuclear genomes in neuroblastoma (NB) is unknown. PROCEDURE: Variants of the mt and nuclear genomes from tumor, blood cells, and consecutive plasma samples of five patients with metastatic NB that relapsed or progressed were analyzed. Targeted parallel...

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Identifiers

PMID: 35899825
DOI: 10.1002/cnr2.1687
PMCID: PMC9875664

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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