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Article

Single-cell next-generation sequencing of circulating tumor cells in patients with neuroblastoma.

Cancer science - 1 Apr 2023

Kojima Masato, Harada Takanori, Fukazawa Takahiro, Kurihara Sho, Touge Ryo, Saeki Isamu, Takahashi Shinya, Hiyama Eiso

Abstract excerpt

Circulating tumor cells (CTCs) derived from any tumor tissue could contribute to metastasis and resistance to cancer treatments. In this study, we performed single-cell next-generation sequencing of CTCs and evaluated their usefulness for characterizing tumor biology and the mechanisms of metastasis in neuroblastomas (NB). We aimed to isolate CTCs from 10 patients with NB at diagnosis before any treatments and...

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Identifiers

PMID: 36571449
DOI: 10.1111/cas.15707
PMCID: PMC10067419

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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