Article
The emerging role of LRRK2 in tauopathies.
Clinical science (London, England : 1979) - 15 Jul 2022
Herbst Susanne, Lewis Patrick A, Morris Huw R
Abstract excerpt
Parkinson's disease (PD) is conventionally described as an α-synuclein aggregation disorder, defined by Lewy bodies and neurites, and mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common autosomal dominant cause of PD. However, LRRK2 mutations may be associated with diverse patho...
Topics
- Humans
- Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
- Mutation
- Parkinson Disease
- Tauopathies
- alpha-Synuclein