Article
Contribution of rare mutational outcomes to broadly neutralizing antibodies.
Acta biochimica et biophysica Sinica - 25 May 2022
Feng Anqi, Hao Qian, Yeap Leng-Siew
Abstract excerpt
Antibodies are important immune molecules that are elicited by B cells to protect our bodies during viral infections or vaccinations. In humans, the antibody repertoire is diversified by programmed DNA lesion processes to ensure specific and high affinity binding to various antigens. Broadly neutralizing antibodies (bnAbs) are antibodies that have strong neutralizing activities against different variants of a...
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