Article
Haplotype structure and divergence at human and chimpanzee serotonin transporter and receptor genes: implications for behavioral disorder association analyses.
Molecular biology and evolution - 1 Jul 2010
Claw Katrina G, Tito Raul Y, Stone Anne C, Verrelli Brian C
Abstract excerpt
Genetic variation in the human serotonin system has long-been studied because of its functional consequences and links to various behavior-related disorders and it being routinely targeted in research and development for drug therapy. However, aside from clinical studies, little is known about this genetic diversity and how it differs within and between human populations with respect to haplotype structure, which...
Topics
- Animals
- Biological Evolution
- Genetic Variation
- Genetics, Behavioral
- Haplotypes
- Humans
- Linkage Disequilibrium
- Pan troglodytes
- Polymerase Chain Reaction
- Polymorphism, Single Nucleotide
