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Article

Notch signaling in female cancers: a multifaceted node to overcome drug resistance

1 Jan 2021

Abstract excerpt

Drug resistance is one of the main challenges in cancer therapy, including in the treatment of female-specific malignancies, which account for more than 60% of cancer cases among women. Therefore, elucidating the underlying molecular mechanisms is an urgent need in gynecological cancers to foster novel therapeutic approaches. Notably, Notch signaling, including either receptors or ligands, has emerged as a...

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PMID: 35582386
DOI: 10.20517/cdr.2021.53

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