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Translational drugs targeting cancer stem cells in triple-negative breast cancer

13 Jun 2025

Abstract excerpt

Triple-negative breast cancer (TNBC) is defined by the lack of expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). It is unresponsive to targeted therapy and is associated with a high degree of malignancy, a high propensity for metastasis, high recurrence rates, and poor prognosis. In the modern concept of cancer biology, a subset of cancer cells...

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PMID: 40687439
DOI: 10.1016/j.omton.2025.201008

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