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Mechanisms of Drug Resistance in Ovarian Cancer and Associated Gene Targets

18 Dec 2022

Abstract excerpt

In the United States, over 100,000 women are diagnosed with a gynecologic malignancy every year, with ovarian cancer being the most lethal. One of the hallmark characteristics of ovarian cancer is the development of resistance to chemotherapeutics. While the exact mechanisms of chemoresistance are poorly understood, it is known that changes at the cellular and molecular level make chemoresistance challenging to...

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PMID: 36551731
DOI: 10.3390/cancers14246246

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