Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Drug Resistance in Non-Small Cell Lung Cancer: A Potential for NOTCH Targeting?

24 Jul 2018

Abstract excerpt

Drug resistance is a major cause for therapeutic failure in non-small cell lung cancer (NSCLC) leading to tumor recurrence and disease progression. Cell intrinsic mechanisms of resistance include changes in the expression of drug transporters, activation of pro-survival, and anti-apoptotic pathways, as well as non-intrinsic influences of the tumor microenvironment. It has become evident that tumors are composed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer Genomics and Diagnostics
Share to Epigenetics and DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30087852
DOI: 10.3389/fonc.2018.00267

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Drug Resistance in Non-Small Cell Lung Cancer: A Potential for NOTCH Targeting?PMID 30087852Read ↗

Are we missing the target? Cancer stem cells and drug resistance in non-small cell lung cancer.Semantic proximity Read ↗

Lung cancer stem cells: The root of resistance.Semantic proximity Read ↗

A role for cancer stem cells in drug resistance and metastasis in non-small-cell lung cancerSemantic proximity Read ↗

Concise Review: Resistance to Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer: The Role of Cancer Stem CellsSemantic proximity Read ↗

Comprehensive review of drug resistance in mammalian cancer stem cells: implications for cancer therapySemantic proximity Read ↗

Drug resistance and Cancer stem cellsSemantic proximity Read ↗

Non-Small Cell Lung Cancer Targeted Therapy: Drugs and Mechanisms of Drug Resistance.Semantic proximity Read ↗

Intricate relationship between cancer stemness, metastasis, and drug resistanceSemantic proximity Read ↗

Impact of microRNAs in Resistance to Chemotherapy and Novel Targeted Agents in Non-Small Cell Lung CancerSemantic proximity Read ↗

Oncogenic Mutations and the Tumor Microenvironment: Drivers of Non-Small Cell Lung Cancer ProgressionSemantic proximity Read ↗

Overview of the multifaceted resistances toward EGFR-TKIs and new chemotherapeutic strategies in non-small cell lung cancer.Semantic proximity Read ↗

Targeting Lung Cancer Stem Cells: Research and Clinical ImpactsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.