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Article

The paradigm of drug resistance in cancer: an epigenetic perspective

1 Apr 2022

Abstract excerpt

Innate and acquired resistance towards the conventional therapeutic regimen imposes a significant challenge for the successful management of cancer for decades. In patients with advanced carcinomas, acquisition of drug resistance often leads to tumor recurrence and poor prognosis after the first therapeutic cycle. In this context, cancer stem cells (CSCs) are considered as the prime drivers of therapy resistance...

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PMID: 35438143
DOI: 10.1042/bsr20211812

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