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Article

A practical framework RNMF for exploring the association between mutational signatures and genes using gene cumulative contribution abundance.

Cancer medicine - 1 Nov 2022

Li Zhenzhang, Liang Haihua, Zhang Shaoan, Luo Wen

Abstract excerpt

BACKGROUND: Mutational signatures are somatic mutation patterns enriching operational mutational processes, which can provide abundant information about the mechanism of cancer. However, understanding of the pathogenic biological processes is still limited, such as the association between mutational signatures and genes. METHODS: We developed a simple and practical R package called RNMF...

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PMID: 35575002
DOI: 10.1002/cam4.4717
PMCID: PMC9636515

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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