Article

Deep Learning model accurately classifies metastatic tumors from primary tumors based on mutational signatures

2022-10-03

Abstract excerpt

Metastatic propagation is the leading cause of death for most cancers. Prediction and elucidation of metastatic process is crucial for the therapeutic treatment of cancers. Even though somatic mutations have been directly linked to tumorigenesis and metastasis, it is less explored whether the metastatic events can be identified through genomic mutation signatures, a concise representation of the mutational process...

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Literature Corpus work: 61f84520-d329-5e5d-8003-d08113bc687f
DOI: 10.1101/2022.09.29.510207

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