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Integrated cohort of esophageal squamous cell cancer reveals genomic features underlying clinical characteristics

7 Sept 2022

Abstract excerpt

Esophageal squamous cell cancer (ESCC) is the major pathologic type of esophageal cancer in Asian population. To systematically evaluate the mutational features underlying clinical characteristics, we establish the integrated dataset of ESCC-META that consists of 1930 ESCC genomes from 33 datasets. The data process pipelines lead to well homogeneity of this integrated cohort for further analysis. We identified 11...

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PMID: 36071046
DOI: 10.1038/s41467-022-32962-1

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