Article

DGAT-onco: A powerful method to detect oncogenes by integrating differential mutational analysis and functional impacts of somatic mutations

2020-02-16

Abstract excerpt

<h4>Motivation</h4> Oncogenes are genes whose malfunctions play critical roles in cancer development, and their discovery is a major aim of cancer mechanisms study. By counting the mutation frequency, oncogenes have been identified with frequent mutations, while it is believed that many more oncogenes could be discovered by differential mutational profile analysis. However, it is common that current methods only...

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Literature Corpus work: a022ec2a-1990-516f-96f6-57cf7ebb5ff5
DOI: 10.1101/2020.02.15.947085

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