Article
Influence network model uncovers relations between biological processes and mutational signatures.
Genome medicine - 6 Mar 2023
Amgalan Bayarbaatar, Wojtowicz Damian, Kim Yoo-Ah, Przytycka Teresa M
Abstract excerpt
BACKGROUND: There has been a growing appreciation recently that mutagenic processes can be studied through the lenses of mutational signatures, which represent characteristic mutation patterns attributed to individual mutagens. However, the causal links between mutagens and observed mutation patterns as well as other types of interactions between mutagenic processes and molecular pathways are not fully...
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