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Article

Human Induced Pluripotent Stem Cell-Derived Macrophages Share Ontogeny with MYB-Independent Tissue-Resident Macrophages.

Stem cell reports - 14 Feb 2017

Buchrieser Julian, James William, Moore Michael D

Abstract excerpt

Tissue-resident macrophages, such as microglia, Kupffer cells, and Langerhans cells, derive from Myb-independent yolk sac (YS) progenitors generated before the emergence of hematopoietic stem cells (HSCs). Myb-independent YS-derived resident macrophages self-renew locally, independently of circulating monocytes and HSCs. In contrast, adult blood monocytes, as well as infiltrating, gut, and dermal macrophages,...

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Share to Core Binding Factor Alpha 2 Subunit
Share to Embryoid Bodies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Erythrocytes

Share to Gene Knockout Techniques

Share to Genes, myb

Share to Granulocytes

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Source

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Identifiers

PMID: 28111278
DOI: 10.1016/j.stemcr.2016.12.020
PMCID: PMC5312255

Genes

MYB
RUNX1
SPI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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