Article

Yolk-Sac-Derived Macrophages Progressively Expand in the Mouse Kidney with Age

2019-10-21

Abstract excerpt

Renal macrophages represent a highly heterogeneous and specialized population of myeloid cells with mixed developmental origins from the yolk-sac and hematopoietic stem cells (HSC). They promote both injury and repair by regulating inflammation, angiogenesis, and tissue remodeling. Recent reports highlight differential roles for ontogenically distinct renal macrophage populations in disease. However, little is kno...

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Literature Corpus work: 6f6308d8-e409-582d-9e4d-1cfde7bde710
DOI: 10.1101/811927

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