Article
[Polymorphisms of FcγRIIA, FcγRIIIA and FcγRIIB in patients with immune thrombocytopenia and their clinical significance].
Zhongguo shi yan xue ye xue za zhi - 1 Feb 2013
Zhu Ying, Zhuang Yun, Yang Guo-Hua, Qiang Xi-Feng, Yang Lei, Shen Yun-Feng
Abstract excerpt
This study was aimed to investigate the correlation of FcγR polymorphisms with the susceptibility, severity and efficacy of immunotherapy for patients with immune thrombocytopenia (ITP). PCR and DNA sequencing were used to determine the polymorphisms of FcγRIIA, FcγRIIIA and FcγRIIB in 44 ITP patients, and in 97 healthy control subjects. The results indicated that FcγRIIIA-158V/F polymorphisms between patients...
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