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Article

Evaluation of the relationship between SORL1 gene polymorphism and Parkinson's disease in the Chinese population.

Neuroscience letters - 1 May 2022

Wang Ying, Luan Mengting, Xue Li, Jin Jianing, Xie Anmu

Abstract excerpt

OBJECTIVE: There is increasing evidence that lysosomal pathway dysfunction is closely linked to the pathogenesis of Parkinson's disease (PD). Considering the relationship between sortilin-related receptor 1 (SORL1) and lysosomal dysfunction, the abnormal aggregation of misfolded proteins in neurodegenerative disorders, especially in PD, and that glial cell-derived neurotrophic factor (GDNF) is the most effective...

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PMID: 35364126
DOI: 10.1016/j.neulet.2022.136602

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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