Article
Genetic analysis of the LRP10 gene in Chinese patients with Parkinson's disease.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 Mar 2023
Song Na, Wang Yan, Zhou Liangxing, Zhang Junli, Wu Fan, Li Mengpeng, Wang Wei, Liu Yanming, Lu Xianjie, Chen Qingfa, Zhang Nan, Yan Yongjian, Han Fabin
Abstract excerpt
BACKGROUND: Parkinson's disease (PD) is a neurodegenerative disorder characterized by resting tremor, bradykinesia, muscle rigidity, and abnormal gait. The low-density lipoprotein receptor-related protein 10 (LRP10) was recently shown to be a causal gene for PD, and different ethnic cohorts have distinct frequencies and spectrum of LRP10 variants. METHODS: We sequenced the full coding regions and exon-intron...
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