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Article

Prosaposin variants in sporadic, familial, and early-onset Parkinson's disease: a Taiwanese case-control study and meta-analysis.

Scientific reports - 26 Jan 2024

Kuo Ming-Che, Chu Yung-Tsai, Su Yu-An, Chen Meng-Ling, Wu Ruey-Meei

Abstract excerpt

Polymorphisms in the PSAP gene, which encodes prosaposin and is involved in the lysosomal function, yielded conflicting results regarding the association with Parkinson's disease (PD). Therefore, this study aims to investigate the role of PSAP in familial PD (FPD), early onset PD (EOPD) with age at onset before 50 years old, and sporadic PD (SPD) among Taiwanese population, and summarize relevant studies via...

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Source

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Identifiers

PMID: 38278831
DOI: 10.1038/s41598-024-51646-y
PMCID: PMC10817969

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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