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Article

Influence of the presence of mannose-binding lectin polymorphisms on the occurrence of leishmaniasis: a systematic review and meta-analysis.

Anais brasileiros de dermatologia - 1 Jan 2000

Vital Wonei de Seixas, Santos Felipe Jules de Araújo, Gonçalves Maurício Leandro Fernandes, Wyrepkowski Claudia Dantas Comandolli, Ramasawmy Rajendranath, Furtado Silvania da Conceição

Abstract excerpt

BACKGROUND: Leishmaniasis is caused by an intracellular protozoan of the Leishmania genus. Mannose-binding lectin (MBL) is a serum complement protein and recognizes lipoprotein antigens in protozoa and the bacterial plasma membrane. Nucleotide variants in the promoter region and exon 1 of the MBL gene can influence its expression or change its molecular structure. OBJECTIVE: To evaluate, through a systematic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35331599
DOI: 10.1016/j.abd.2021.08.004
PMCID: PMC9133304

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