Article
Functional variations in MBL2 gene are associated with cutaneous leishmaniasis in the Amazonas state of Brazil.
Genes and immunity - 1 Jun 2015
de Araujo F J, Mesquita T G, da Silva L D O, de Almeida S A, de S Vital W, Chrusciak-Talhari A, de O Guerra J A, Talhari S, Ramasawmy R
Abstract excerpt
Functional variations in the mannose-binding lectin (MBL2) gene causing low levels of serum MBL are associated with susceptibility to numerous infectious diseases. We investigated whether there is genetic association of MBL2 variant alleles with cutaneous leishmaniasis (CL) caused by Leishmania guyanensis. We used PCR-restriction fragment length polymorphism to genotype six MBL2 variants, three in the promoter...
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