Article
Analysis of HIV-1 integrase genotypes and polymorphisms among integrase inhibitors-based antiretroviral treatment naïve patients in South Sudan.
Journal of medical virology - 1 Jul 2022
Giovanetti Marta, Farcomeni Stefania, Sernicola Leonardo, Virtuoso Sara, Fontanelli Sulekova Lucia, Maggiorella Maria T, Buttò Stefano, Taliani Gloria, Ciccozzi Massimo, Borsetti Alessandra
Abstract excerpt
HIV-1 genetic diversity and drug resistance mutations remain public health challenges especially in regions where treatment is limited. The aim of this study was to characterize the HIV-1 integrase (IN) subtype and the possible occurrence of drug-resistance mutations or polymorphisms in resource-poor settings in South Sudan. Dried blood spots from integrase inhibitor treatment (Integrase strand transfer inhibitor...
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