Article
HIV Type 1 genetic diversity and naturally occurring polymorphisms in HIV type 1 Kenyan isolates: implications for integrase inhibitors.
AIDS research and human retroviruses - 1 Aug 2012
Nyamache Anthony Kebira, Muigai Anne W T, Nganga Zipporah, Khamadi Samoel A
Abstract excerpt
Little is known about the extent and predictors of polymorphisms potentially influencing susceptibility to HIV integrase inhibitors. HIV-1 genetic diversity and drug resistance are major challenges in patient management globally. To evaluate HIV genetic diversity and drug resistance-associated mutations within a Nairobi cohort, genetic analysis of the HIV-1 pol-integrase gene regions was performed on samples...
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