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Article

Pre-Treatment Integrase Inhibitor Resistance and Natural Polymorphisms among HIV-1 Subtype C Infected Patients in Ethiopia.

Viruses - 30 Mar 2022

Arimide Dawit Assefa, Szojka Zsófia Ilona, Zealiyas Kidist, Gebreegziabxier Atsbeha, Adugna Fekadu, Sasinovich Sviataslau, Björkman Per, Medstrand Patrik

Abstract excerpt

Dolutegravir-based antiretroviral therapy (ART) has been scaled up in many developing countries, including Ethiopia. However, subtype-dependent polymorphic differences might influence the occurrence of HIV-drug-resistance mutations (HIVDRMs). We analyzed the prevalence of pre-treatment integrase strand transfer inhibitor (INSTI) HIVDRMs and naturally occurring polymorphisms (NOPs) of the integrase gene, using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35458459
DOI: 10.3390/v14040729
PMCID: PMC9029575

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