Article
Low level of HIV-1C integrase strand transfer inhibitor resistance mutations among recently diagnosed ART-naive Ethiopians.
Scientific reports - 21 Apr 2023
Kiros Mulugeta, Tefera Dessalegn Abeje, Andualem Henok, Geteneh Alene, Tesfaye Abebech, Woldemichael Tamirayehu Seyoum, Kidane Eleni, Alemayehu Dawit Hailu, Maier Melanie, Mihret Adane, Abegaz Woldaregay Erku, Mulu Andargachew
Abstract excerpt
With the widespread use of Integrase strand transfer inhibitors (INSTIs), surveillance of HIV-1 pretreatment drug resistance is critical in optimizing antiretroviral treatment efficacy. However, despite the introduction of these drugs, data concerning their resistance mutations (RMs) is still limited in Ethiopia. Thus, this study aimed to assess INSTI RMs and polymorphisms at the gene locus coding for Integrase...
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