Article
Prevalence of integrase strand transfer inhibitor resistance mutations in antiretroviral-naive HIV-1-infected individuals in Cameroon.
The Journal of antimicrobial chemotherapy - 1 Jan 2021
Wenk Benjamin M, Mbunkah Herbert A, Nsanwe Ndi N, Mbu Eyongetah T, Besong Lydia M, Sama Bella A, Orock Emmanuel, Leemann Christine, Metzner Karin J
Abstract excerpt
OBJECTIVES: In Cameroon, the integrase (IN) strand transfer inhibitor (INSTI) dolutegravir was recently introduced for the treatment of HIV-1 infection. Since pretreatment HIV-1 drug resistance can jeopardize the success of ART, and considering the high heterogeneity of circulating HIV-1 subtypes in Cameroon, we investigated the prevalence of pretreatment HIV-1 resistance to INSTIs. METHODS: Fingerprick dried...
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