Article
HIV Type 1 Integrase Natural Polymorphisms in Viral Variants Circulating in FSU Countries.
Current HIV research - 23 Nov 2017
Lapovok Ilya, Laga Vita, Kazennova Elena, Bobkova Marina
Abstract excerpt
BACKGROUND: Natural variability of integrase (IN) across HIV-1 variants may influence the emergence of resistant viruses. The most apparent explanation of this fact is the IN polymorphism and the associated differences in codon usage, which in turn, influence the probability and the terms of DRMs acquisition. Possible mechanisms by which polymorphisms affect DRMs emergence remain disputed and should still be...
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